This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Immunogen sequence: MSGFICPKCK KESQIFPPTT GGAELMCQDL EVPLLGRVPL DPLIGKNCDK GQSFFIDAPD SPATLAYRSI IQRIQEFCNL HQSKEENLIS S
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 80%.
Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication. Negatively regulates cilium formation and structure.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Cytosolic Fe-S cluster assembly factor NUBP1; NBP 1; NUBP1; nucleotide binding protein (e.coli MinD like); nucleotide binding protein 1 (E.coli MinD like); nucleotide binding protein 1 (MinD homolog, E. coli); Nucleotide-binding protein 1
Gene Aliases: NBP; NBP1; NBP35; NUBP1
UniProt ID: (Human) P53384
Entrez Gene ID: (Human) 4682