FIGURE: 1 / 7
Immunogen sequence: MSRPVRNRK VVDYSQFQES DDADEDYGRD SGPPTKKIRS SPREAKNKRR SGKNSQEDSE DSEDKDVKTK KDDSHSAEDS EDEKEDHKNV RQQRQAASKA ASKQREMLME DVGSEEEQEE EDEAPFQEKD SGSDEDFLME DDDDSDYGSS KKKNKKMVKK SKPERKEKKM PKPRLKATVT PSPVKGKGKV GRPTASKASK EKTPSPKEED EEPESPPEKK TSTSPPPEKS GDEGSEDEAP SGED (1-243 aa encoded by BC000805)
This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle.
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Protein Aliases: nuclear casein kinase and cyclin-dependent kinase substrate 1; Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1; nuclear ubiquitous casein kinase and cyclin-dependent kinase substrate; P1; potential LAG1 interactor
Gene Aliases: JC7; NUCKS; NUCKS1
UniProt ID: (Human) Q9H1E3
Entrez Gene ID: (Human) 64710