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Invitrogen
NUDT3 Polyclonal Antibody
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Product Details
PA5-30435
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein encompassing a sequence within the center region of human NUDT3. The exact sequence is proprietary.
Conjugate
Form
Liquid
Concentration
0.14 mg/mL
Amount
14 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7, with 1% BSA, 20% glycerol
Contains
0.025% ProClin 300
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Recommended positive controls: IMR32.
Predicted reactivity: Mouse (97%), Rat (96%), Dog (99%), Pig (99%), Chicken (95%), Rhesus Monkey (100%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
NUDT3 belongs to the MutT, or Nudix, protein family. Nudix proteins act as homeostatic checkpoints at important stages in nucleoside phosphate metabolic pathways, guarding against elevated levels of potentially dangerous intermediates, like 8-oxo-dGTP, which promotes AT-to-CG transversions (Safrany et al., 1998 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ap6A hydrolase; diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1; Diadenosine hexaphosphate hydrolase; Diphosphoinositol polyphosphate phosphohydrolase 1; DIPP-1; Endopolyphosphatase; m7GpppN-mRNA hydrolase; m7GpppX diphosphatase; Nucleoside diphosphate-linked moiety X motif 3; nudix (nucleoside diphosphate linked moiety X)-type motif 3; Nudix motif 3; unnamed protein product
Gene Aliases: DIPP; DIPP-1; DIPP1; NUDT3
UniProt ID: (Human) O95989
Entrez Gene ID: (Human) 11165
magnesium ion binding
endopolyphosphatase activity
protein binding
zinc ion binding
diphosphoinositol-polyphosphate diphosphatase activity
pyrophosphatase activity
hydrolase activity
manganese ion binding
bis(5'-adenosyl)-hexaphosphatase activity
bis(5'-adenosyl)-pentaphosphatase activity
metal ion binding
inositol diphosphate tetrakisphosphate diphosphatase activity
inositol diphosphate pentakisphosphate diphosphatase activity
inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity
inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity
5'-(N(7)-methyl 5'-triphosphoguanosine)-[mRNA] diphosphatase activity
5'-(N(7)-methylguanosine 5'-triphospho)-[mRNA] hydrolase activity
cell-cell signaling
diadenosine polyphosphate catabolic process
diphosphoinositol polyphosphate metabolic process
diphosphoinositol polyphosphate catabolic process
RNA decapping
diadenosine pentaphosphate catabolic process
diadenosine hexaphosphate catabolic process
adenosine 5'-(hexahydrogen pentaphosphate) catabolic process
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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