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Invitrogen
NUDT6 Polyclonal Antibody
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FIGURE: 1 / 8
NUDT6 Antibody (PA5-102309) in IHC (P)
Immunohistochemistry analysis of NUDT6 in mouse testis tissue. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. Samples were incubated with NUDT6 polyclonal antibody (Product # PA5-102309) using a dilution of 1:100 (4°C overnight) followed by HRP conjugated anti-Rabbit secondary antibody.
Product Details
PA5-102309
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human NUDT6(Accession P53370), corresponding to amino acid residues V144-E194.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total NUDT6.
Target Information
NUDT6 (nudix (nucleoside diphosphate linked moiety X)-type motif 6), also known as Antisense basic fibroblast growth factor or GFG-1, is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. The gene encoding NUDT6 is a FGF-2 gene antisense transcript, and NUDT6 is believed to regulate FGF-2 expression. FGF-2 is a mutifunctional heparin-binding growth factor important to angiogenesis, neuroectoderm development and wound healing. NUDT6 is expressed as two isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: anti-sense basic fibroblast growth factor B; Antisense basic fibroblast growth factor; Antisense basic fibroblast growth factor B; FAD diphosphatase NUDT6; NADH pyrophosphatase NUDT6; Nucleoside diphosphate-linked moiety X motif 6; nudix (nucleoside diphosphate linked moiety X)-type motif 6; Nudix hydrolase 6; Nudix motif 6; Protein GFG; unnamed protein product
Gene Aliases: ASFGF2; Asfgf2b; FGF-AS; FGF2AS; Gfg; GFG-1; GFG1; NUDT6
UniProt ID: (Human) P53370, (Rat) P70563, (Mouse) Q8CH40
Entrez Gene ID: (Human) 11162, (Rat) 207120, (Mouse) 229228
hydrolase activity
NADH pyrophosphatase activity
ADP-ribose diphosphatase activity
FAD diphosphatase activity
NAD binding
thiamine-pyrophosphatase activity
8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity
UDP-2,3-diacylglucosamine hydrolase activity
bis(5'-nucleosyl)-tetraphosphatase activity
dATP pyrophosphohydrolase activity
pyrophosphatase activity
dihydroneopterin monophosphate phosphatase activity
dihydroneopterin triphosphate pyrophosphohydrolase activity
dITP diphosphatase activity
dTTP diphosphatase activity
XTP diphosphatase activity
ATP-dependent 5'-3' DNA helicase activity
phosphocholine hydrolase activity
nucleotide phosphatase
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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