The protein encoded by this gene is a member of the formin-binding-protein family. The protein contains an N-terminal Fer/Cdc42-interacting protein 4 (CIP4) homology (FCH) domain followed by a coiled-coil domain, a proline-rich motif, a second coiled-coil domain, a Rho family protein-binding domain (RBD), and a C-terminal SH3 domain. This protein binds sorting nexin 2 (SNX2), tankyrase (TNKS), and dynamin; an interaction between this protein and formin has not been demonstrated yet in human.
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Protein Aliases: numb homolog (Drosophila)-like; numb homolog-like; Numb-like protein; Numb-R; Numb-related protein
Gene Aliases: CAG3A; CTG3a; NBL; NUMB-R; NUMBL; NUMBLIKE; NUMBR; TNRC23
Molecular Function: signaling molecule