Immunogen sequence: VTQISVDLMD DYPASDPRWA ESVPEEAPGF SNTSLIILHQ LEDKMKAHSF LMDFIHQVGL FGRLGSFPVR GTPMATRLLL CEHAEKLSAA IVLKNHHSRL SDLVNTAILI ALNKREYEIP SNLTPA
Highest antigen sequence identity to the following orthologs: Mouse - 84%, Rat - 83%.
Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 133 kDa nucleoporin; Nuclear pore complex protein Nup133; nucleoporin 133kD; nucleoporin 133kDa; Nucleoporin Nup133
Gene Aliases: hNUP133; NUP133
UniProt ID: (Human) Q8WUM0
Entrez Gene ID: (Human) 55746