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Proteintech
NUP153 Polyclonal Antibody
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Product Details
14189-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
NUP153 Fusion Protein Ag5519 (1125-1475 aa encoded by BC052965)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Amount
25.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: EEPKCQPVF SFGNSEQTKD ENSSKSTFSF SMTKPSEKES EQPAKATFAF GAQTSTTADQ GAAKPVFSFL NNSSSSSSTP ATSAGGGIFG SSTSSSNPPV ATFVFGQSSN PVSSSAFGNT AESSTSQSLL FSQDSKLATT SSTGTAVTPF VFGPGASSNN TTTSGFGFGA TTTSSSAGSS FVFGTGPSAP SASPAFGANQ TPTFGQSQGA SQPNPPGFGS ISSSTALFPT GSQPAPPTFG TVSSSSQPPV FGQQPSQSAF GSGTTPNSSS AFQFGSSTTN FNFTNNSPSG VFTFGANSST PAASAQPSGS GGFPFNQSPA AFTVGSNGKN VFSSSGTSFS GRKIKTAVRR RK (1125-1475 aa encoded by B C052965)
Target Information
Nuclear pore complexes regulate the transport of macromolecules between the nucleus and cytoplasm. They are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. Nucleoporins are glycoproteins found in nuclear pores and contain characteristic pentapeptide XFXFG repeats as well as O-linked N-acetylglucosamine residues oriented towards the cytoplasm. The protein encoded by this gene has three distinct domains: a N-terminal region containing a pore targeting and an RNA-binding domain, a central region containing multiple zinc finger motifs, and a C-terminal region containing multiple XFXFG repeats. Alternative splicing results in multiple transcript variants of this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 153 kDa nucleoporin; nuclear pore complex protein hnup153; Nuclear pore complex protein Nup153; nucleoporin 153kD; nucleoporin 153kDa; Nucleoporin Nup153; unnamed protein product
Gene Aliases: B130015D15Rik; C88147; HNUP153; N153; NUCZINK; NUP153
UniProt ID: (Human) P49790, (Mouse) E9Q3G8
Entrez Gene ID: (Human) 9972, (Rat) 25281, (Mouse) 218210
DNA binding
protein binding
nuclear localization sequence binding
zinc ion binding
structural constituent of nuclear pore
identical protein binding
protein anchor
metal ion binding
molecular condensate scaffold activity
nucleocytoplasmic transporter activity
Ran GTPase binding
porin activity
transporter
RNA export from nucleus
protein import into nucleus
nucleocytoplasmic transport
protein transport
viral entry into host cell
negative regulation of RNA export from nucleus
mRNA transport
nuclear pore complex assembly
viral penetration into host nucleus
amyloid fibril formation
transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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