Immunogen sequence: PATTLYAHFE QANIKTQLQQ LGVTLSMTRT ELSPAQIKQL LQNPPAGVDP IIWEQAKVDN PDSEKLIPVP MVGFKELLRR LKVQDQMTKQ HQTR
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 100%.
The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. This gene encodes a member of the phe-gly repeat-containing nucleoporin subset.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 54 kDa nucleoporin; Nuclear pore complex protein Nup54; nucleoporin 54kD; nucleoporin 54kDa; Nucleoporin Nup54; Nucleoporin p54
Gene Aliases: 3110079L04Rik; 54kDa; NUP54
Molecular Function: transporter