This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated. View Details
MA1-071 detects nuclear pore-O-linked glycoprotein from rat, amphibian and yeast.
MA1-071 has been successfully used in Western blot, immunofluorescence and immunoprecipitation procedures. By Western blot, this antibody detects up to eight different proteins from the nuclear pore complex (NPC) of approximately 210, 180, 145, 100, 63, 58, 54 and 45 kDa. Immunofluorescence staining of NPC O-linked glycoproteins with MA1-071 results in exclusive labeling of the NPC proteins on a wide variety of mammalian cells as well as S. cerevisiae and Xenopus. Labeling occurs exclusively at the NPC with most of the labeling at the cytoplasmic and nucleoplasmic margins.
Microinjected MA1-071 inhibits both protein import and RNA export in Xenopus oocytes.
The MA1-071 immunogen is pore complex-lamina fraction purified from rat liver nuclear envelopes.
SDS3 is a subunit of the histone deacetylase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 62 kDa nucleoporin; DKFZp547L134; FLJ20822; FLJ43869; MGC841; nuclear pore glycoprotein 62; Nuclear pore glycoprotein p62; Nucleoporin Nup62; nucleoporin p62
Gene Aliases: Np62; Nup62
UniProt ID: (Rat) P17955
Entrez Gene ID: (Rat) 65274
Molecular Function: transporter