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Product Details
PA5-53674
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human NUP93. Recombinant protein control fragment (Product #RP-91837).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2644904
Product Specific Information
Immunogen sequence: VERNLQEIQQ AGERLRSRTL TRTSQETADV KASVLLGSRG LDISHISQRL ESLSAATTFE PLEPVKDTDI QGFLKNEKDN ALLSAIEESR KRTFGMAEEY HRESMLVEWE QVKQRI^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
Target Information
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. This gene encodes a nucleoporin protein that localizes both to the basket of the pore and to the nuclear entry of the central gated channel of the pore. The encoded protein is a target of caspase cysteine proteases that play a central role in programmed cell death by apoptosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 93 kDa nucleoporin; CBP-interacting protein 4; Nuclear pore complex protein Nup93; nucleoporin 93kDa; Nucleoporin Nup93
Gene Aliases: 2410008G02Rik; Cip4; KIAA0095; NIC96; NPHS12; NUP93
UniProt ID: (Human) Q8N1F7, (Mouse) Q8BJ71, (Rat) Q66HC5
Entrez Gene ID: (Human) 9688, (Mouse) 71805, (Rat) 291874
positive regulation of defense response to virus by host
mRNA export from nucleus
tRNA export from nucleus
protein import into nucleus
nuclear envelope organization
mitotic nuclear envelope disassembly
regulation of glucose transport
viral process
protein sumoylation
poly(A)+ mRNA export from nucleus
viral transcription
gene silencing by RNA
nuclear pore complex assembly
positive regulation of SMAD protein import into nucleus
SMAD protein signal transduction
renal system development
glomerular visceral epithelial cell development
intracellular transport of virus
glomerular visceral epithelial cell migration
mitophagy in response to mitochondrial depolarization
xenophagy
regulation of cellular response to heat
negative regulation of hydrogen peroxide-induced cell death
transport
protein transport
mRNA transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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