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          • Primary Antibodies ›
          • NRG2 Antibodies

          Osenses

          Neuregulin 2 Polyclonal Antibody

          2 References
          View all (9) NRG2 antibodies

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          Cite Neuregulin 2 Polyclonal Antibody

          Additional Information:
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          Product Details

          OSN00056W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:300-1:2,000
          -

          Immunohistochemistry (IHC)

          1:300-1:2,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 2 publications 2 publications
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from extracellular domain of mouse Neuregulin-2 (NRG2) conjugated to an immunogenic carrier protein was used as the antigen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          Specificity of this antibody: NRG2.

          Target Information

          Neuregulin 2 is a novel member of the neuregulin family of growth and differentiation factors. Through interaction with the Erbb family of receptors, NRG2 induces the growth and differentiation of epithelial, neuronal, glial, and other types of cells. The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1, another member of the neuregulin family of ligands. NRG1 and NRG2 mediate distinct biological processes by acting at different sites in tissues and eliciting different biological responses in cells. The gene is located close to the region for demyelinating Charcot-Marie-Tooth disease locus, but is not responsible for this disease. Alternative transcripts encoding distinct isoforms have been described.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: divergent of neuregulin-1; neural- and thymus-derived activator for ErbB kinases; NTAK alpha1; Pro-neuregulin-2, membrane-bound isoform; Pro-NRG2; unnamed protein product

          View more View less

          Gene Aliases: DON1; HRG2; NRG2; NTAK; NTAK_alpha2a

          View more View less

          UniProt ID: (Human) O14511, (Rat) O35569

          View more View less

          Entrez Gene ID: (Human) 9542, (Rat) 432361, (Mouse) 100042150

          View more View less

          Function(s)
          receptor binding growth factor activity epidermal growth factor-activated receptor activity epidermal growth factor receptor binding ErbB-3 class receptor binding growth factor intercellular signal molecule
          Process(es)
          signal transduction nervous system development intracellular signal transduction ERBB4 signaling pathway animal organ development epidermal growth factor receptor signaling pathway peptidyl-tyrosine phosphorylation
          It has to be done as per old AB suggested Products section.

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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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