|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||A synthetic peptide corresponding to residues in human Neurensin-2|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS with 50% glycerol|
|Contains||0.1% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||1:500-1:1000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
This antibody detects endogenous protein at a molecular weight of 22 kDa.
Purity is >95% by SDS-PAGE.
Neurensin-2 (NRSN2) is a 204 amino acid multi-pass membrane protein belonging to the VMP family that may be involved in the transport and maintenance of vesicles. Expressed in brain, Neurensin-2 localizes to cell bodies of hippocampus, diagonal band, amygdaloid nucleus, and habenula nucleus, and is a potential tumor suppressor gene and candidate biomarker for long-term survival in patients with hepatocellular carcinoma (HCC). The gene encoding Neurensin-2 maps to human chromosome 20, which comprises approximately 2% of the human genome, contains nearly 63 million bases and encodes over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought important for seminal production and may be potential targets for male contraception.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.