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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • NRGN Antibodies

          Proteintech

          Neurogranin Polyclonal Antibody

          3 References
          View all (18) NRGN antibodies

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          Cite Neurogranin Polyclonal Antibody

          • Antibody Testing Data (19)
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
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          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          FIGURE: 1 / 19

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          Neurogranin Antibody (10440-1-AP) in IHC (P)

          Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using (Product # 10440-1-AP) (Neurogranin antibody) at dilution of 1:200 (under 0x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Neurogranin Antibody in Western Blot (WB)
          Neurogranin Antibody in Immunoprecipitation (IP)
          Neurogranin Polyclonal Antibody

          Product Details

          10440-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          -

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          -
          View 1 publication 1 publication

          Immunoprecipitation (IP)

          0.5-4.0 µg
          -

          Not applicable (N/A)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          Neurogranin Fusion Protein Ag0676 (1-78 aa encoded by BC002835)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.53 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: MDCCTENAC SKPDDDILDI PLDDPGANAA AAKIQASFRG HMARKKIKSG ERGRKGPGPG GPGGAGVARG GAGGGPSGD (1-78 aa encoded by BC002835)

          Target Information

          Neurogranin is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: calmodulin-binding protein; Neurogranin; neurogranin (protein kinase C substrate, RC3); Ng; postsynaptic spine 1; protein kinase C substrate; Protein kinase C substrate 7.5 kDa protein; RC3

          View more View less

          Gene Aliases: 0710001B06Rik; AI838505; hng; NG; NG/RC3; NRGN; Pss1; R75334; RC3

          View more View less

          UniProt ID: (Human) Q92686, (Mouse) P60761, (Rat) Q04940

          View more View less

          Entrez Gene ID: (Human) 4900, (Mouse) 64011, (Rat) 64356

          View more View less

          Function(s)
          calmodulin binding phosphatidylinositol-3,4,5-trisphosphate binding phosphatidic acid binding
          Process(es)
          nervous system development intracellular signal transduction positive regulation of long-term synaptic potentiation signal transduction associative learning telencephalon development
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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