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Invitrogen
Neurophysin II Polyclonal Antibody
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Product Details
PA5-148460
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Goat
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Neurophysin II, Cys20-Tyr164
Conjugate
Form
Lyophilized
Concentration
0.2 mg/mL
Amount
100 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS with trehalose
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute at 0.2 mg/mL in sterile PBS.
Target Information
Neurophysin II is a carrier protein encoded by the AVP gene located on chromosome 20 in humans. It plays a crucial role in the transport and storage of the hormone vasopressin, also known as antidiuretic hormone (ADH). Vasopressin is essential for regulating water balance in the body by promoting water reabsorption in the kidneys. Neurophysin II binds to vasopressin in the neurosecretory vesicles of the hypothalamus and facilitates its transport to the posterior pituitary gland, where vasopressin is stored and later released into the bloodstream. Mutations in the AVP gene can result in conditions such as familial neurohypophyseal diabetes insipidus, characterized by an inability to concentrate urine and maintain proper water balance. Neurophysin II, therefore, is integral to maintaining homeostasis through its role in the vasopressin pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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