PA5-27882 targets NRF2 in IF, ChIP, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-27882 immunogen is recombinant fragment corresponding to a region within amino acids 108 and 413 of Human NRF2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995 [PubMed 7868116]).
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Protein Aliases: erythroid derived 2; HEBP1; like 2; NF-E2-related factor 2; NFE2-related factor 2; NRF2; nuclear factor; Nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2-like 2; Nuclear factor, erythroid derived 2, like 2
Gene Aliases: AI194320; HEBP1; NFE2L2; Nrf-2; NRF2