Immunogen sequence: VFCGRIQLFL ARLFPLSEKS GLNLQSQFNL ENVTVFNTNE QESTLGQKHT EDREEGMDVE EGEMGDEEAP TTCSIPIDYN LYRKFWS
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 46%.
P84/N5-5E10 recognizes an 84 kDa nuclear matrix protein. Initially isolated by its interaction with the amino terminal region of the retinoblastoma protein, it has been used extensively as a nuclear-specific marker in both immunofluorescence and cell fractionation studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HPR1; hTREX84; Nuclear matrix protein p84; P84; P84N5; THO complex subunit 1; Tho1
Gene Aliases: HPR1; P84; P84N5; THOC1
UniProt ID: (Human) Q96FV9
Entrez Gene ID: (Human) 9984
Molecular Function: nucleic acid binding