Immunogen sequence: KILMGNEELT RLWNLCPDNM EACKSETREH MPTLEEFFEE AIEQADPENM VENEYKAVNN SNYGWRALRL LARRSPHFFQ PTNQQFKSLP EYLENMVIKL AKELPPPSEE IKTGEDEDEE DNDALLK
Highest antigen sequence identity to the following orthologs: Mouse - 98%, Rat - 88%.
P84/N5-5E10 recognizes an 84 kDa nuclear matrix protein. Initially isolated by its interaction with the amino terminal region of the retinoblastoma protein, it has been used extensively as a nuclear-specific marker in both immunofluorescence and cell fractionation studies.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HPR1; hTREX84; Nuclear matrix protein p84; P84; P84N5; THO complex subunit 1; Tho1
Gene Aliases: 3110002N20Rik; AW107452; HPR1; LRRGT00070; NMP-84; P84; P84N5; THOC1
Molecular Function: nucleic acid binding