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Invitrogen
Nucleostemin Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
FIGURE: 1 / 7
Nucleostemin Antibody (PA5-92992) in ICC/IF
Immunofluorescence analysis of Guanine nucleotide-binding protein-like 3 was performed using 70% confluent log phase U-2 OS cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with Nucleostemin Polyclonal Antibody (Product # PA5-92992) at 1:100 dilution in... View More
Product Details
PA5-92992
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human GNL3 (NP_9965621)
Conjugate
Form
liquid
Concentration
0.2 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20° C, Avoid Freeze/Thaw Cycles
Shipping conditions
Wet ice
RRID
AB_2806575
Product Specific Information
Immunogen sequence: MTCHKRYKIQ KKVREHHRKL RKEAKKRGHK KPRKDPGVPN SAPFKEALLR EAELRKQRLE ELKQQQKLDR QKELEKKRKL ETNPDIKPSN VEPMEKEFGL CKTENKAKSG KQNSKKLYCQ ELKKVIEASD VVLEVLDARD PLGCRCPQVE EAIVQSGQKK LVLILNKSDL VPKENLESWL NYLKKELPTV VFRASTKPKD KGKITKRVKA KKNAAPFRSE VCFGKEGLWK LLGGFQETCS; Positive Samples: 293T; Cellular Location: Nucleus, nucleolus
Target Information
Arylsulfatase F, also known as ARSF, is a 590 amino acid secretory protein that belongs to the sulfatase family of bone and cartilage matrix proteins. Arylsulfatase F uses calcium as a cofactor to catalyze reactions that are important in maintaining correct bone composition. The activity of Arylsulfatase F, unlike that of other family members, such as Arylsulfatase E, is not inhibited by warfarin. The gene encoding Arylsulfatase F maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes. In conjunction with chromosome Y, chromosome X is responsible for sex determination. There are a number of conditions related to an abnormal number and combination of sex chromosomes, some of which include Turner's syndrome, color blindness, hemophilia and Duchenne muscular dystrophy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: E2-induced gene 3 protein; estradiol-induced nucleotide binding protein; guanine nucleotide binding protein-like 3 (nucleolar); Guanine nucleotide-binding protein-like 3; MGC800; NNP47; Novel nucleolar protein 47; Nucleolar GTP-binding protein 3; Nucleostemin
Gene Aliases: C77032; E2IG3; GNL3; NNP47; NS
UniProt ID: (Human) Q9BVP2
Entrez Gene ID: (Human) 26354
cell proliferation
positive regulation of telomere maintenance
positive regulation of protein sumoylation
regulation of cell proliferation
ribosome biogenesis
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of protein localization to chromosome, telomeric region
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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