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Rockland
OASL Polyclonal Antibody
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FIGURE: 1 / 3
OASL Antibody (600-401-DF6) in ICC/IF
Immunofluorescence Microscopy of Rabbit anti-OASL antibody. Tissue: HepG2. Primary antibody: OASL antibody at 20 µg/mL. Secondary antibody: Fluorescein rabbit secondary antibody at 1:20,000. Localization: OASL is nuclear and cytoplasmic. Staining: OASL as red fluorescent signal.
Product Details
600-401-DF6
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Anti-OASL antibody was prepared from whole rabbit serum produced by repeated immunizations with a 17 amino acid peptide near the N-terminus of human OASL.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.2
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
2-prime,5-prime oligoadenylates (2-5As) bind to and activate RNase L, leading to degradation of RNA and inhibition of protein synthesis. 2-5As are produced by 2-5A synthetases (OASs), a highly-conserved family of interferon-induced enzymes. The predicted 514-amino acid human p59OASL (2-5A synthetases-like) protein shares a highly conserved N-terminal domain with other OASs. The C-terminal portion of p59OASL contains 2 ubiquitin-like domains. p59OASL is expressed in most tissues, with the highest levels in hematopoietic tissues, colon, and stomach.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: 2',5'-oligoadenylate synthetase-like 9; 2'-5' oligoadenylate synthetase-like 1; 2'-5'-OAS-related protein; 2'-5'-OAS-RP; 2'-5'-oligoadenylate synthase-like protein; 2'-5'-oligoadenylate synthase-like protein 1; 2'-5'-oligoadenylate synthetase-like; 2,5-oligoadenylate synthetase-like 9; 59 kDa 2'-5'-oligoadenylate synthase-like protein; 59 kDa 2'-5'-oligoadenylate synthetase-like protein; p59 OASL; p59OASL; Thyroid receptor-interacting protein 14; TR-interacting protein 14
Gene Aliases: 7530414C13Rik; OASL; Oasl1; oasl9; OASLd; p59 OASL; p59-OASL; p59OASL; TRIP-14; TRIP14
UniProt ID: (Human) Q15646, (Rat) G3V645, (Mouse) Q8VI94
Entrez Gene ID: (Human) 8638, (Rat) 304545, (Mouse) 231655
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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