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Proteintech
OATP14 Polyclonal Antibody
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Product Details
17163-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OATP14 Fusion Protein Ag10573 (290-391 aa encoded by BC022461)
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Amount
45 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VPFWYLPKS LPRSQSREDS NSSSEKSKFI IDDHTDYQTP QGENAKIMEM ARDFLPSLKN LFGNPVYFLY LCTSTVQFNS LFGMVTYKPK YIEQQYGQSS SRA (290-391 aa encoded by BC022461)
Target Information
This gene encodes a member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of thyroid hormones in brain tissues. This protein has particularly high affinity for the thyroid hormones thyroxine, tri-iodothyronine and reverse tri-iodothyronine. Polymorphisms in the gene encoding this protein may be associated with fatigue and depression in patients suffering from hyperthyroidism. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: BAST1; BBB-specific anion transporter type 1; blood-brain barrier specific anion transporter; Blood-brain barrier-specific anion transporter 1; OAT-RP-5; OATP-14; OATP-F; OATP-F; solute carrier family 21 (organic anion transporter), member 14; OATP-RP5; OATP transporter family member; OATP1C1; OATP2; Organic anion transporter 1C1; Organic anion transporter 2; Organic anion transporter F; Organic anion transporter polypeptide-related protein 5; organic anion transporting polypeptide 14; Organic anion-transporting polypeptide 14; solute carrier family 21 (organic anion transporter), member 14; Solute carrier family 21 member 14; Solute carrier organic anion transporter family member 1C1; Thyroxine transporter; unnamed protein product
Gene Aliases: Bsat1; OATP-14; OATP-F; OATP-RP5; OATP1; OATP14; OATP1C1; Oatp2; OATPF; OATPRP5; SLC21A14; SLCO1C1
UniProt ID: (Human) Q9NYB5, (Rat) Q9EPZ7, (Mouse) Q9ERB5
Entrez Gene ID: (Human) 53919, (Rat) 84511, (Mouse) 58807
ion transport
lipid transport
bile acid and bile salt transport
sodium-independent organic anion transport
transmembrane transport
thyroid hormone transport
transport across blood-brain barrier
positive regulation of thyroid hormone generation
transport
anion transmembrane transport
organic acid transmembrane transport
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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