Search Thermo Fisher Scientific
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Product Details
31626-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OATP1A2 fusion protein Ag34497
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice
Product Specific Information
Immunogen sequence: FLMTCENSSV VGINTSYEGI PQDLYVENDI FADCNVDCNC PSKIWDPVCG NNGLSYLSAC LAGCETSIGT GINMVFQNCS CIQTSGNSSA VLGLCDKGPD CSLMLQYF
Target Information
The organic anion transporting polypeptides, OATP-A (also designated OATP1, OATP1A2 and SLC21A3) and OATP-C (also designated OATP2, SLC21A6 and LST1), mediate hepatic uptake of cardiac glycosides. The expression of OATP-C, but not OATP-A, is inducible by phenobarbital and pregnenolone-16a-carbonitrile, resulting in the increased capacity of the liver to extract cardiac glycosides from the plasma. OATP-A is expressed in liver and kidney and helps mediate sodium-independent uptake of the anionic steroid conjugates dehydroepiandrosterone sulfate, estradiol-17-glucuronide and prostaglandin. OATP-C is exclusively expressed in liver and is localized to the basolateral hepatocyte membrane.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: Brain digoxin carrier protein; Brain-specific organic anion transporter; OATP-1; OATP-A; OATP-B1; OATP1A2; organic anion transporter 2; organic anion transporting polypeptide A; Organic anion-transporting polypeptide 1; SO1A2; Sodium-independent organic anion transporter; Sodium-independent organic anion transporter 1; Sodium-independent organic anion-transporting polypeptide 1; Sodium-independent organic anion-transporting polypeptide 2; solute carrier family (organic anion transporter) member 1; solute carrier family (organic anion transporter) member 3; solute carrier family 21 (organic anion transporter), member 1; solute carrier family 21 (organic anion transporter), member 3; solute carrier family 21 (organic anion transporter), member 5; Solute carrier family 21 member 1; Solute carrier family 21 member 3; Solute carrier family 21 member 5; solute carrier family 21, member 1; Solute carrier organic anion transporter family member 1A1; Solute carrier organic anion transporter family member 1A2; Solute carrier organic anion transporter family member 1A4; solute carrier organic anion transporter family, member 1A2; solute carrier organic anion transporter family, member 1a4
Gene Aliases: A530084B21; OATP; OATP-1; OATP-A; OATP1; Oatp1a1; OATP1A2; Oatp1a4; Oatp2; Slc21a1; SLC21A3; Slc21a5; Slco1a1; SLCO1A2; Slco1a4
UniProt ID: (Human) P46721, (Mouse) Q9QXZ6, (Rat) P46720, (Rat) O35913
Entrez Gene ID: (Human) 6579, (Mouse) 28248, (Rat) 50572, (Rat) 170698
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support