Immunogen sequence: QGKDTKASDN ERKVMDEANL EFLNNGEHFV PSAGTDSKTC NLDMQDNAAA
This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of endogenous and xenobiotic compounds and plays a critical role in bile acid and bilirubin transport. Mutations in this gene are a cause of Rotor type hyperbilirubinemia. Alternative splicing of this gene and the use of alternative promoters results in transcript variants encoding different isoforms that differ in their tissue specificity. [provided by RefSeq, Mar 2017]
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Protein Aliases: Liver-specific organic anion transporter 2; liver-specific organic anion transporter 3TM13; LST-2; OATP-8; OATP1B3; OATP8; Organic anion transporter 8; organic anion transporter LST-3c; Organic anion-transporting polypeptide 8; SLC21A8; solute carrier family 21 (organic anion transporter), member 8; Solute carrier family 21 member 8; Solute carrier organic anion transporter family member 1B3; solute carrier organic anion transporter family, member 1B3
Gene Aliases: HBLRR; LST-2; LST-3TM13; LST2; LST3; OATP-8; OATP1B3; OATP8; SLC21A8; SLCO1B3
UniProt ID: (Human) Q9NPD5
Entrez Gene ID: (Human) 28234
Molecular Function: transporter