Predicted to react with Mouse and Rat samples.
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: antizyme 2; AZ2; ODC-Az 2; Ornithine decarboxylase antizyme 2; Seizure-related protein 15
Gene Aliases: AZ-2; AZ2; OAZ2; Oaz2-ps; RGD1562933; Sez15
Molecular Function: protein-binding activity modulator