Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
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Protein Aliases: 84 kDa outer dense fiber protein; cancer/testis antigen 134; Cenexin; cenexin 1; ODF2; ODF2/1; ODF2/2; ODF84; outer dense fiber of sperm tail 2; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; sperm outer dense fiber major protein 2; sperm tail structural protein; testis tissue sperm-binding protein Li 51e; testis-specific autoantigen
Gene Aliases: AI848335; CT134; KKT4; MMTEST29; ODF2; ODF2/1; ODF2/2; ODF84