This Antibody was verified by Relative expression to ensure that the antibody binds to the antigen stated. View Details
Immunogen sequence: HKRGMKGDTV NVRRSVRVKT KNPPHCLEIT PPSSEKLVSV MRLSDLSTED DDSGHCKMNR YDKKIDSLMN AVGCLKSEVK MQKGERQMAK RFLEERKEEL EEVAHELAET EHENTVLRHN IERMKEEKDF TILQKKHLQQ EKE
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
Seems to be a major component of sperm tail outer dense fibers (ODF). ODFs are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. May have a modulating influence on sperm motility. Functions as a general scaffold protein that is specifically localized at the distal/subdistal appendages of mother centrioles. Component of the centrosome matrix required for the localization of PLK1 and NIN to the centrosomes. Required for the formation and/or maintenance of normal CETN1 assembly.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: cancer/testis antigen 134; Cenexin; cenexin 1; Outer dense fiber of sperm tails protein 2; outer dense fiber of sperm tails, 84-kD; Outer dense fiber protein 2; RP11-187B3.1, CT134, ODF2/1, ODF2/2, ODF84, cancer/testis antigen 134; sperm tail structural protein; testis tissue sperm-binding protein Li 51e
Gene Aliases: CT134; ODF2; ODF2/1; ODF2/2; ODF84
UniProt ID: (Human) Q5BJF6
Entrez Gene ID: (Human) 4957