Recommended positive controls: mouse brain, rat brain.
Predicted reactivity: Mouse (87%), Rat (86%), Pig (92%), Bovine (92%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
OGFOD1, a member of the 2-OG-Fe(II) dioxygenase family, plays an important role in ischemic survival and stress. It is an oxidoreductase containing a Prolyl 4-hydroxylase alpha subunit. An OGFOD1 iron binding residue is required for ATPAF1 gene expression. As a novel stress granule component, OGFOD1 plays important proapoptotic roles in the regulation of translation and HRI-mediated phosphorylation of eIF2alpha in cells.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: 2-oxoglutarate and iron-dependent oxygenase domain containing 1; 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 1; Prolyl 3-hydroxylase OGFOD1; Termination and polyadenylation 1 homolog; TPA1, termination and polyadenylation 1, homolog; uS12 prolyl 3-hydroxylase
Gene Aliases: 4930415J21Rik; AA387199; AA939912; AW061076; KIAA1612; mKIAA1612; OGFOD1; RGD1308848; TPA1