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Proteintech
OLFM1 Polyclonal Antibody
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Product Details
10079-1-AP
Product Specifications
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OLFM1 Fusion Protein Ag0125 (1-169 aa encoded by BC000189)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This antibody is specific for isoform 3 and isoform 4 (AMY) of Olfm1 with native molecular weights of 54 kDa and 16 kDa respectively. AMY may have an essential role in nerve tissue.
Immunogen sequence: MPGRWRWQR DMHPARKLLS LLFLILMGTE LTQNKRENKA EKMGGPESER KTTGEKTLNE LPLFCLEAHA GSLALPRMCS PNPNPAVGLC RPAYPQSPSP GAAQTISQSL LERFCMASRR EVFLAPGRPG GGWWLCTVAG QMHSFMCTHT HTHAHTGEQI PAEKSQPGPD (1-169 aa encoded by BC000189)
Target Information
The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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