Search
Invitrogen
OLIG3 Polyclonal Antibody
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
FIGURE: 1 / 1
OLIG3 Antibody (PA5-110060) in WB
Western blot analysis of OLIG3 in extracts of various cell lines. Samples were incubated with OLIG3 Polyclonal antibody (Product # PA5-110060) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.
Product Details
PA5-110060
Product Specifications
Species Reactivity
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 163-272 of human OLIG3 (NP_786923.1).
Conjugate
Form
Liquid
Concentration
1.43 mg/mL
Amount
143 µg
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.01% thimerosal
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: TVGHSAGHPA HAANSVHPVH PILGGALSSG NASSPLSAAS LPAIGTIRPP HSLLKAPSTP PALQLGSGFQ HWAGLPCPCT ICQMPPPPHL SALSTANMAR LSAESKDLLK
Target Information
Oligodendrocyte transcription factor 3 (OLIG3) is a gene located on chromosome 6q23.2, encoding a basic helix-loop-helix (bHLH) transcription factor that is involved in the regulation of neural development. OLIG3 is a member of the OLIG family, which plays a significant role in the differentiation and maturation of oligodendrocytes, the myelinating cells of the central nervous system. This transcription factor is crucial for the specification and development of certain neuronal subtypes, contributing to the formation and maintenance of the central nervous system's architecture. OLIG3's activity influences gene expression related to neural proliferation, survival, and differentiation. Although less studied than OLIG1 and OLIG2, OLIG3's expression patterns suggest its involvement in neural patterning and potential roles in neuronal disorders. Research continues to explore the mechanisms through which OLIG3 affects neural development and its implications in neuropathologies and regenerative medicine.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
References (0)
Have you cited this product in a publication?
Let us know so we can reference it here.
Bioinformatics
Protein Aliases: basic helix-loop-helix domain-containing class B protein 7; bHLHb7; bHLHe20oligo3; Class B basic helix-loop-helix protein 7; Oligo3; oligodendrocyte transcription factor 2; Oligodendrocyte transcription factor 3; Oligodendrocyte-specific bHLH transcription factor 3
Gene Aliases: Bhlhb7; bHLHe20; Olig3
UniProt ID: (Mouse) Q6PFG8
Entrez Gene ID: (Mouse) 94222, (Rat) 293012
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
regulation of gene expression
spinal cord motor neuron cell fate specification
spinal cord motor neuron differentiation
spinal cord motor neuron migration
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support