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Invitrogen
OLIG3 Polyclonal Antibody
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Product Details
PA5-41688
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human OLIG3 (aa 1-50).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: MNSDSSSVSS RASSPDMDEM YLRDHHHRHH HHQESRLNSV SSTQGDMMQK
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 85%
Target Information
Oligodendrocyte transcription factor 3 (OLIG3) is a gene located on chromosome 6q23.2, encoding a basic helix-loop-helix (bHLH) transcription factor that is involved in the regulation of neural development. OLIG3 is a member of the OLIG family, which plays a significant role in the differentiation and maturation of oligodendrocytes, the myelinating cells of the central nervous system. This transcription factor is crucial for the specification and development of certain neuronal subtypes, contributing to the formation and maintenance of the central nervous system's architecture. OLIG3's activity influences gene expression related to neural proliferation, survival, and differentiation. Although less studied than OLIG1 and OLIG2, OLIG3's expression patterns suggest its involvement in neural patterning and potential roles in neuronal disorders. Research continues to explore the mechanisms through which OLIG3 affects neural development and its implications in neuropathologies and regenerative medicine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: bHLHb7; bHLHe20; bHLHe20oligo3; Class B basic helix-loop-helix protein 7; Class E basic helix-loop-helix protein 20; Oligo3; Oligodendrocyte transcription factor 3
Gene Aliases: BHLHB7; BHLHE20; OLIG3
UniProt ID: (Human) Q7RTU3
Entrez Gene ID: (Human) 167826
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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