Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
1:500-1:1,000 | View 5 publications 5 publications |
Immunohistochemistry (IHC) |
- | View 2 publications 2 publications |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:50-1:500 | - |
Flow Cytometry (Flow) |
0.2 µg/1x10^6 cells | - |
Immunoprecipitation (IP) |
0.5-4.0 µg | - |
Product Specifications | |
---|---|
Species Reactivity |
Human |
Published species |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
OLR1 Fusion Protein Ag2437 (1-273 aa encoded by BC022295) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.46 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.1% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MTFDDLKIQ TVKDQPDEKS NGKKAKGLQF LYSPWWCLAA ATLGVLCLGL VVTIMVLGMQ LSQVSDLLTQ EQANLTHQKK KLEGQISARQ QAEEASQESE NELKEMIETL ARKLNEKSKE QMELHHQNLN LQETLKRVAN CSAPCPQDWI WHGENCYLFS SGSFNWEKSQ EKCLSLDAKL LKINSTADLD FIQQAISYSS FPFWMGLSRR NPSYPWLWED GSPLMPHLFR VRGAVSQTYP SGTCAYIQRG AVYAENCILA AFSICQKKAN LRAQ (1-273 aa encoded by BC022295)
LOX-1 (lectin-like oxidized LDL receptor -1) is a 40-50 kDa type II membrane glycoprotein class E scavenger receptor expressed by endothelial cells, macrophages, activated platelets and smooth muscle cells. LOX-1 binds to a wide range of ligands, including oxidized low-density lipoprotein (oxLDL), hypochlorite modified high-density lipoprotein (HDL), aged /apoptotic cells, activated platelets and bacteria, reflecting its versatile physiological functions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: C-type lectin domain family 8 member A; hLOX 1; hLOX-1; hLOX1; Lectin-like oxidized LDL receptor 1; Lectin-type oxidized LDL receptor 1; LOX 1; LOX-1; ox LDL receptor 1; Ox-LDL receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; Oxidized low-density lipoprotein receptor 1; Oxidized low-density lipoprotein receptor 1, soluble form; scavenger receptor class E, member 1; sLOX 1; soluble LOX 1
Gene Aliases: CLEC8A; LOX1; LOXIN; OLR1; SCARE1; SLOX1
UniProt ID: (Human) P78380
Entrez Gene ID: (Human) 4973
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