PA1-4559 detects kappa Opioid Receptor from human samples.
PA1-4559 has been successfully used in Western blotting applications. This antibody will detect a dominant band of ~46 kDa representing the monomer form of OPRK1, and may also detect dimmers or trimers as heterodimerization and homodimerization is common
The PA1-4559 immunogen is a synthetic peptide corresponding to residues D(366) P A Y L R D I D G M N L P V(380) of the human KOR-1 protein.
G protein-coupled receptors (GPCRs) are the largest family of membrane receptors that activate intracellular signaling cascades and undergo endocytosis, recycling, or degradation upon stimulation. The mu, delta and kappa opioid receptors are GPCRs of the
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Protein Aliases: K-OR-1; kappa opioid receptor; Kappa-type opioid receptor; Opiate receptor, kappa-1; opioid receptor, kappa 1; Opioid Receptor, Kappa-1; OPRK1
Gene Aliases: K-OR-1; KOR; KOR-1; OPRK; OPRK1
UniProt ID: (Human) P41145
Entrez Gene ID: (Human) 4986