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Invitrogen
OPRM1 Polyclonal Antibody
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Product Details
PA5-34042
Product Specifications
Species Reactivity
Bat,
Bovine,
Dog,
Hamster,
Human,
Non-human primate,
Pig
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic 18 amino acid peptide from C-terminus of human OPRM1 / Mu Opioid Receptor.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
50 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS
Contains
0.1% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Percent identity with other species by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Marmoset, Dog, Bat, Bovine, Hamster, Elephant, Panda, Pig (100%).
Target Information
The OPRM1 gene encodes the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family. There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: G-protein coupled receptor; GPCR; GPCR; MOR-1K1; hMOP; KIAA0403; M-OR-1; MOP; MOR-1; MOR-1C; MOR1; MOR3; Mu opiate receptor; Mu opioid receptor; mu opioid receptor hMOR-1a; Mu-type opioid receptor; mu-type opioid receptor 1; mu-type opioid receptor-like; Opioid mu receptor; Opioid Receptor; opioid receptor, mu 1; OTTHUMP00000017463; unnamed protein product
Gene Aliases: I79_001179; LMOR; M-OR-1; MOP; MOR; MOR1; OPRM; OPRM1
UniProt ID: (Pig) Q95247, (Bovine) P79350, (Human) P35372
Entrez Gene ID: (Pig) 396802, (Bovine) 281958, (Human) 4988, (Dog) 484041, (Chinese hamster) 100770962
G-protein alpha-subunit binding
G-protein coupled receptor activity
voltage-gated calcium channel activity
morphine receptor activity
beta-endorphin receptor activity
opioid receptor activity
protein binding
G-protein coupled peptide receptor activity
G-protein beta-subunit binding
neuropeptide binding
G-protein coupled receptor
transmembrane signal receptor
adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway
phospholipase C-activating G-protein coupled receptor signaling pathway
sensory perception of pain
opioid receptor signaling pathway
negative regulation of cAMP-mediated signaling
negative regulation of nitric oxide biosynthetic process
positive regulation of neurogenesis
negative regulation of cytosolic calcium ion concentration
negative regulation of Wnt protein secretion
positive regulation of ERK1 and ERK2 cascade
calcium ion transmembrane transport
cellular response to morphine
regulation of N-methyl-D-aspartate selective glutamate receptor activity
neuropeptide signaling pathway
signal transduction
G-protein coupled receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway
sensory perception
negative regulation of cell proliferation
behavioral response to ethanol
regulation of cellular response to stress
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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