Immunogen sequence: IYVIIKALVT IPETTFQTVS WHFCIALGYT NSCLNPVLYA FLDENFKRCF REFCIPTSSN IEQQNSTRIR QNTRDHPSTA NTVDRTNHQL ENLEAETAPL P; Positive Samples: Mouse brain, Rat brain; Cellular Location: Cell membrane, Cytoplasm, Multi-pass membrane protein
This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia.
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Protein Aliases: M-OR-1; MOP receptor; MOR-1; mu opioid receptor splice variant mMOR-1Z; mu opioid receptor splice variant rMOR-1S; mu opioid receptor splice variant rMOR-1Z; Mu-type opioid receptor; MUOR1; Opioid receptor B
Gene Aliases: M-OR-1; MOP-R; Mor; MOR-1; MOR-1O; MORA; muOR; Oprm; Oprm1; Oprrm1; Ror-b