PA1-32782 detects Olfactory receptor OR10R2 from human samples.
G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more thana thousandmembers currently predicted to exist.All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This "turn-off" activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates.
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Protein Aliases: Olfactory receptor 10R2; Olfactory receptor OR1-8; olfactory receptor, family 10, subfamily R, member 2
Gene Aliases: OR1-8; OR10R2; OR10R2Q
UniProt ID: (Human) Q8NGX6
Entrez Gene ID: (Human) 343406