Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
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Protein Aliases: novel 7 transmembrane receptor (rhodopsin family) protein; Olfactory receptor 2T12; Olfactory receptor 2T33; Olfactory receptor 2T8; Olfactory receptor OR1-56; Olfactory receptor OR1-57; olfactory receptor, family 2, subfamily T, member 12; olfactory receptor, family 2, subfamily T, member 33; olfactory receptor, family 2, subfamily T, member 8 pseudogene
Gene Aliases: OR1-56; OR1-57; OR2T12; OR2T33; OR2T8; OR2T8P
Molecular Function: transmembrane signal receptor