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Proteintech
ORAI2 Polyclonal Antibody
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Product Details
20592-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
ORAI2 Fusion Protein Ag14540 (176-254 aa encoded by BC069270)
Conjugate
Form
Liquid
Concentration
0.17 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VDARRQPGP PPGPGSHTGW QAALVSTIIM VPVGLIFVVF TIHFYRSLVR HKTERHNREI EELHKLKVQL DGHERSLQVL (176-254 aa encoded by BC069270)
Target Information
Antigen stimulation of immune cells triggers Ca++ entry through Ca++ release-activated Ca++ (CRAC) channels. ORAI2 is one of two mammalian homologs to ORAI1, a recently identified four-transmembrane spanning protein that is an essential component of CRAC. Like ORAI1, ORAI2 has been shown to function as a highly selective Ca++ plasma membrane channel that is gated through interactions with STIM1, the store-activated endoplasmic reticulum Ca++ sensor, although at a lesser efficacy than ORAI1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: calcium release-activated calcium channel 2; CAP-binding protein complex interacting protein 2; CAP-binding protein complex-interacting protein 2; H_NH0514P08.8; Protein orai-2; putative protein ORAI2-2; Transmembrane protein 142B
Gene Aliases: A730041O15Rik; C7orf19; CBCIP2; MEM142B; ORAI2; PP1729; TMEM142B
UniProt ID: (Human) Q96SN7, (Mouse) Q8BH10
Entrez Gene ID: (Human) 80228, (Mouse) 269717
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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