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Invitrogen
ORAI3 Polyclonal Antibody
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Product Details
PA5-109271
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide within Human Orai-3 aa 11-60
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol, 0.2% BSA
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles, store in dark
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive Control: Raji, A549, MG-63, SH-SY-5Y, rat brain tissue, human liver cancer tissue, human kidney tissue, human placenta tissue, mouse testis tissue.
Target Information
ORAI3 is a protein coding gene that is involved in calcium signaling and regulation of calcium homeostasis. It is a member of the ORAI family of proteins that form calcium release-activated calcium (CRAC) channels in the plasma membrane of cells. These channels are activated by depletion of calcium from the endoplasmic reticulum, leading to an influx of calcium ions into the cytoplasm. ORAI3 has been implicated in a variety of physiological processes, including T-cell activation, muscle contraction, and neurotransmitter release. Dysregulation of ORAI3 expression or function has been associated with various diseases, including immune disorders, cancer, and cardiovascular disease
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Protein orai-3; Transmembrane protein 142C
Gene Aliases: ORAI3; TMEM142C
UniProt ID: (Human) Q9BRQ5
Entrez Gene ID: (Human) 93129
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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