Recommended positive controls: A431, H1299, HeLa, HepG2.
Predicted reactivity: Mouse (100%), Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Histone deacetylase 2 (HDAC2), or transcriptional regulator homolog RPD3 L1, is highly homologous to the yeast transcription factor RPD3 (reduced potassium dependency 3) gene. As in yeast, human HDA2 is likely to be involved in regulating chromatin structure during transcription. It has been implicated to associate with YY1, a mammalian zinc-finger transcription factor, which negatively regulates transcription by tethering RPD3 to DNA as a cofactor. This process is highly concerved from yeast to human.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
Protein Aliases: homolog of latheo, Drosophila; IMAGE50150; Origin recognition complex subunit 3; Origin recognition complex subunit Latheo; origin recognition complex, subunit 3 honolog; OTTHUMP00000040611; RP3-486L4.1
Gene Aliases: LAT; LATHEO; ORC3; ORC3L
UniProt ID: (Human) Q9UBD5
Entrez Gene ID: (Human) 23595