This antibody is predicted to react with bovine, canine and rat based on sequence homology.
The origin recognition complex is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. This gene encodes a subunit of the ORC complex. Several alternatively spliced transcript variants, some of which encode the same protein, have been reported for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HSORC4; ORC4; ORC4L; ORC4P; Origin recognition complex subunit 4; origin recognition complex, subunit 4 (yeast homolog)-like; origin recognition complex, subunit 4 homolog; Origin recognition complex, subunit 4, S. cerevisiae, homolog-like; origin recognition complex, subunit 4-like (yeast)
Gene Aliases: mMmORC4; ORC4; ORC4L; ORC4P