PA5-28976 targets ORNT1 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-28976 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 301 of Human ORNT1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
The SLC25A15 gene encodes the mitochondrial ornithine transporter, which transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. This is a vital step in the urea cycle, which serves to eliminate toxic ammonium ions from the breakdown of nitrogen (Camacho et al., 1999 [PubMed 10369256]).
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For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: D13S327; HHH; Mitochondrial ornithine transporter 1; ORC1; ornithine transporter 1; ORNT1; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; Solute carrier family 25 member 15
Gene Aliases: D13S327; HHH; ORC1; ORNT1; SLC25A15; SP1855
UniProt ID: (Human) Q9Y619
Entrez Gene ID: (Human) 10166
Molecular Function: RNA binding protein amino acid transporter calcium-binding protein calmodulin intracellular calcium-sensing protein mitochondrial carrier protein nucleic acid binding ribosomal protein transfer/carrier protein transporter