This target displays homology in the following species: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%; Sheep: 93%
The SLC25A15 gene encodes the mitochondrial ornithine transporter, which transports ornithine across the inner mitochondrial membrane from the cytosol to the mitochondrial matrix. This is a vital step in the urea cycle, which serves to eliminate toxic ammonium ions from the breakdown of nitrogen (Camacho et al., 1999 [PubMed 10369256]).
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Protein Aliases: D13S327; HHH; Mitochondrial ornithine transporter 1; ORC1; ornithine transporter 1; ornithine transporter) member 15; ornithine transporter, mitochondrial 1; ORNT1; solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15; Solute carrier family 25 member 15
Gene Aliases: Ab1-114; BOS_12353; D13S327; D630044L02Rik; HHH; ORC1; ORNT1; SLC25A15; SP1855
Molecular Function: RNA binding protein amino acid transporter calcium-binding protein calmodulin intracellular calcium-sensing protein mitochondrial carrier protein nucleic acid binding ribosomal protein transfer/carrier protein transporter