Sequence homology: Cow: 93%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: ORP-8; OSBP-related protein 8; Oxysterol-binding protein-related protein 8
Gene Aliases: KIAA1451; MST120; MSTP120; ORP8; OSBP10; OSBPL8
UniProt ID: (Human) Q9BZF1
Entrez Gene ID: (Human) 114882