Peptide sequence: HQTPTPNSTG SGHSPPSSSL TSPSHVNLSP NTVPEFSYSS SEDEFYDADE
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%
This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease related chromosomal translocations which result in the expression of chimeric proteins that may promote tumor growth. Alternate splicing results in multiple transcript variants.
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Protein Aliases: FLJ12492; FLJ14629; FLJ14801; FLJ32055; FLJ34384; MGC15035; ORP-9; OSBP-related protein 9; oxysterol binding protein-like 9; Oxysterol-binding protein-related protein 9; RP4-657D16.1
Gene Aliases: ORP-9; ORP9; OSBP4; OSBPL9
UniProt ID: (Human) Q96SU4
Entrez Gene ID: (Human) 114883