PA5-31537 targets OSBP2 in IHC (P) and WB applications and shows reactivity with Human samples.
The PA5-31537 immunogen is recombinant fragment corresponding to a region within amino acids 596 and 835 of Human OSBP2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
Oxysterols are byproducts of cholesterol that can have cytotoxic effects on many cell types. The membrane-bound protein encoded by this gene contains a pleckstrin homology (PH) domain and an oxysterol-binding region. It binds oxysterols such as 7-ketocholesterol and may inhibit their cytotoxicity. Alternate transcriptional splice variants have been observed but have not been fully characterized.
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Protein Aliases: ORP-4; ORP4; OSBP-related protein 4; OSBPL1; OSBPL4; oxysterol binding protein-like 1; oxysterol binding protein-related protein 4; Oxysterol-binding protein 2; Oxysterol-binding protein-related protein 4
Gene Aliases: HLM; KIAA1664; ORP-4; ORP4; OSBP2; OSBPL1; OSBPL4
UniProt ID: (Human) Q969R2
Entrez Gene ID: (Human) 23762