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Proteintech
OSBPL2 Polyclonal Antibody
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Product Details
17217-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OSBPL2 Fusion Protein Ag11031 (129-480 aa encoded by BC004455)
Conjugate
Form
Liquid
Concentration
0.33 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: RMQSVAAFA VSAVASQWER TGKPFNPLLG ETYELIREDL GFRFISEQVS HHPPISAFHS EGLNHDFLFH GSIYPKLKFW GKSVEAEPRG TITLELLKHN EAYTWTNPTC CVHNVIIGKL WIEQYGTVEI LNHRTGHKCV LHFKPCGLFG KELHKVEGHI QDKNKKKLFM IYGKWTECLW GIDPVSYESF KKQERRGDHL RKAKLDEDSG KADSDVADDV PVAQETVQVI PGSKLLWRIN TRPPNSAQMY NFTSFTVSLN ELETGMEKTL PPTDCRLRPD IRGMENGNMD LASQEKERLE EKQREARRER AKEEAEWQTR WFYPGNNPYT GTPDWLYAGD YFERNFSDCP DIY (129-480 aa encoded by BC004455)
Target Information
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ20223; MGC4307; MGC8342; ORP-2; ORP2; ORP2; phospholipid binding protein; OSBP-related protein 2; OSBP6; OSBPL2; oxysterol-binding protein-like 2; Oxysterol-binding protein-related protein 2; RP11-157P1.2; unnamed protein product
Gene Aliases: C130070J12Rik; DFNA67; DNFA67; KIAA0772; mKIAA0772; ORP-2; ORP2; OSBPL2
UniProt ID: (Human) Q9H1P3, (Mouse) Q8BX94
Entrez Gene ID: (Human) 9885, (Rat) 296461, (Mouse) 228983
lipid transport
transport
biological_process
bile acid biosynthetic process
plasma membrane organization
regulation of synaptic vesicle priming
phospholipid transport
cholesterol transport
intracellular cholesterol transport
protein homotetramerization
regulation of presynaptic cytosolic calcium ion concentration
intermembrane lipid transfer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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