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GABA(A) R G2 Polyclonal Antibody
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Product Details
OSG00082W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from aa region 10-100 of mouse GABA A Receptor gamma 2 conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: GABRG2.
Target Information
This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: GABA(A) receptor subunit gamma-2; GABA(A) receptor, gamma 2; GABAAR subunit gamma-2; GABRA2; gamma-aminobutyric acid; gamma-aminobutyric acid A receptor, gamma 2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; gamma-aminobutyric acid (GABA-A) receptor, subunit gamma 2; gamma-aminobutyric acid A receptor, gamma 2; Gamma-aminobutyric acid receptor subunit gamma-2; gamma-aminobutyric acid type A receptor gamma2 subunit; unnamed protein product
Gene Aliases: CAE2; DEE74; ECA2; EIEE74; FEB8; GABAA-R; Gabrg-2; GABRG2; gamma2; GEFSP3
UniProt ID: (Human) P18507, (Mouse) P22723, (Rat) P18508
Entrez Gene ID: (Human) 2566, (Mouse) 14406, (Rat) 29709
transmembrane signaling receptor activity
GABA-A receptor activity
ion channel activity
extracellular ligand-gated ion channel activity
chloride channel activity
protein binding
benzodiazepine receptor activity
GABA-gated chloride ion channel activity
transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential
GABA receptor activity
inhibitory extracellular ligand-gated ion channel activity
ligand-gated ion channel
ion transport
chloride transport
gamma-aminobutyric acid signaling pathway
chemical synaptic transmission
post-embryonic development
adult behavior
ion transmembrane transport
synaptic transmission, GABAergic
regulation of postsynaptic membrane potential
cellular response to histamine
chloride transmembrane transport
inhibitory synapse assembly
transport
signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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