Invitrogen

OSR2 Polyclonal Antibody

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OSR2 Antibody in Western Blot (WB) — Western blot analysis of OSR2 using OSR2 Polyclonal Antibody (Product # PA5-116805) at a 1:1,000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10,000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Product Details

PA5-116805

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	A synthetic peptide corresponding to amino acids 250-312 of human OSR2. View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	1.91 mg/mL
Purification	Affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.01% thimerosal
Storage conditions	-20° C, Avoid Freeze/Thaw Cycles
RRID	AB_2901436

Product Specific Information

Positive Samples: SKOV3, 293T, Mouse testis, Mouse pancreas, Rat large intestine, Rat kidney

Target Information

OSR2 is a mammalian homolog of the Drosophila odd-skipped family of transcription factors.

⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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Bioinformatics

Protein Aliases: odd-skipped related 2; Protein odd-skipped-related 2

Gene Aliases: 5430409I15Rik; OSR2; Osr2A; Osr2B

UniProt ID: (Human) Q8N2R0, (Mouse) Q91ZD1, (Rat) Q6AY34

Entrez Gene ID: (Human) 116039, (Mouse) 107587, (Rat) 315039

Molecular Function: zinc finger transcription factor

negative regulation of transcription from RNA polymerase II promoter metanephros development mesonephros development chondrocyte differentiation transcription from RNA polymerase II promoter positive regulation of cell proliferation embryo development positive regulation of gene expression cell differentiation positive regulation of bone mineralization osteoblast proliferation embryonic forelimb morphogenesis embryonic hindlimb morphogenesis embryonic skeletal limb joint morphogenesis middle ear morphogenesis odontogenesis embryonic digit morphogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis pronephros development positive regulation of epithelial cell proliferation palate development embryonic skeletal joint morphogenesis head development bone morphogenesis eyelid development in camera-type eye embryonic skeletal joint development positive regulation of gastrulation

Process(es)

RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding protein binding sequence-specific DNA binding metal ion binding nucleic acid binding