Invitrogen

OSR2 Polyclonal Antibody

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OSR2 Antibody in Immunofluorescence (IF) — Immunofluorescent staining of OSR2 in human cell line A-431 shows localization to nucleus and plasma membrane. Samples were probed using an OSR2 Polyclonal Antibody (Product # PA5-66585).

OSR2 Antibody in Western Blot (WB) — Western blot analysis of OSR2 in human cell line RT-4. Samples were probed using an OSR2 Polyclonal Antibody (Product # PA5-66585).

Product Details

Tested Applications

Dilution

Immunocytochemistry (ICC)

1-4 µg/mL

Immunofluorescence (IF)

1-4 µg/mL

Western Blot (WB)

1:250 - 1:500

Product Specifications

Species Reactivity

Human

Host / Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human OSR2

Conjugate

Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

RRID

AB_2664032

Product Specific Information

Immunogen sequence: THRSQELRGAA ATEGFLYVLL SHWVFVGAPR PPASDSWKKG LVPSAPPASR KMGSKALPAP IPLHPSLQL

Highest antigen sequence identity to the following orthologs - mouse 31%, rat 31%.

Target Information

OSR2 is a mammalian homolog of the Drosophila odd-skipped family of transcription factors.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Bioinformatics

Protein Aliases: odd-skipped related 2; OSR2; Protein odd-skipped-related 2

Gene Aliases: OSR2

UniProt ID: (Human) Q8N2R0

Entrez Gene ID: (Human) 116039

Molecular Function: nucleic acid binding transcription factor zinc finger transcription factor

Function(s)

negative regulation of transcription from RNA polymerase II promoter metanephros development mesonephros development chondrocyte differentiation transcription from RNA polymerase II promoter positive regulation of cell proliferation embryo development positive regulation of gene expression cell differentiation positive regulation of bone mineralization osteoblast proliferation embryonic forelimb morphogenesis embryonic hindlimb morphogenesis embryonic skeletal limb joint morphogenesis middle ear morphogenesis odontogenesis embryonic digit morphogenesis positive regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter embryonic skeletal system morphogenesis pronephros development positive regulation of epithelial cell proliferation palate development embryonic skeletal joint morphogenesis head development bone morphogenesis eyelid development in camera-type eye embryonic skeletal joint development positive regulation of gastrulation

Process(es)

RNA polymerase II regulatory region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding protein binding sequence-specific DNA binding metal ion binding

OSR2 Polyclonal Antibody

Product Details

Product Specific Information

Target Information

Bioinformatics

Material safety data sheets (MSDS)

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