|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Recombinant fragment corresponding to a region within amino acids 1 and 334 of Human OSTM1|
|Purification||Antigen affinity chromatography|
|Storage buffer||PBS, pH 7, with 1% BSA, 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-29176 targets OSTM1 in WB applications and shows reactivity with Human samples.
The PA5-29176 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 334 of Human OSTM1.
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chloride channel 7 beta subunit; CLCN7 accessory beta subunit; GAIP-interacting protein N terminus; GIPN; grey-lethal osteopetrosis; OPTB5; Osteopetrosis-associated transmembrane protein 1
Gene Aliases: GIPN; GL; HSPC019; OPTB5; OSTM1; UNQ6098/PRO21201
UniProt ID: (Human) Q86WC4
Entrez Gene ID: (Human) 28962
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