PA5-29176 targets OSTM1 in WB applications and shows reactivity with Human samples.
The PA5-29176 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 334 of Human OSTM1.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Chloride channel 7 beta subunit; CLCN7 accessory beta subunit; GAIP-interacting protein N terminus; GIPN; grey-lethal osteopetrosis; OPTB5; Osteopetrosis-associated transmembrane protein 1
Gene Aliases: GIPN; GL; HSPC019; OPTB5; OSTM1; UNQ6098/PRO21201
UniProt ID: (Human) Q86WC4
Entrez Gene ID: (Human) 28962