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Proteintech
OTC Polyclonal Antibody
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Product Details
26470-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
OTC Fusion Protein Ag24186 (35-354 aa encoded by BC074745)
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
30 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: VQLKGRDLL TLKNFTGEEI KYMLWLSADL KFRIKQKGEY LPLLQGKSLG MIFEKRSTRT RLSTETGFAL LGGHPCFLTT QDIHLGVNES LTDTARVLSS MADAVLARVY KQSDLDTLAK EASIPIINGL SDLYHPIQIL ADYLTLQEHY SSLKGLTLSW IGDGNNILHS IMMSAAKFGM HLQAATPKGY EPDASVTKLA EQYAKENGTK LLLTNDPLEA AHGGNVLITD TWISMGQEEE KKKRLQAFQG YQVTMKTAKV AASDWTFLHC LPRKPEEVDD EVFYSPRSLV FPEAENRKWT IMAVMVSLLT DYSPQLQKPK F (35-354 aa encoded by BC074745)
Target Information
This nuclear gene encodes a mitochondrial matrix enzyme. Missense, nonsense, and frameshift mutations in this enzyme lead to ornithine transcarbamylase deficiency, which causes hyperammonemia. Since the gene for this enzyme maps close to that for Duchenne muscular dystrophy, it may play a role in that disease also.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Ornithine carbamoyltransferase, mitochondrial; ornithine transcarbamylase; Ornithine transcarbamylase, mitochondrial; OTCase; sparse fur; unnamed protein product
Gene Aliases: AI265390; OCTD; OTC; OTC1; OTCase; OTCD; Sf; spf
UniProt ID: (Human) P00480, (Mouse) P11725, (Rat) P00481
Entrez Gene ID: (Human) 5009, (Mouse) 18416, (Rat) 25611
urea cycle
liver development
cellular amino acid metabolic process
arginine biosynthetic process
ornithine metabolic process
ornithine catabolic process
midgut development
cellular amino acid biosynthetic process
response to xenobiotic stimulus
response to zinc ion
citrulline biosynthetic process
response to nutrient levels
response to insulin
arginine biosynthetic process via ornithine
anion homeostasis
response to biotin
ammonia homeostasis
protein homotrimerization
response to drug
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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